OSA Research Studies

Clinical Studies About Sleep Apnea

Obstructive sleep apnea (OSA) has been increasingly recognized as a contributor to a myriad of other health conditions. Numerous studies have demonstrated a strong association between OSA and cardiovascular diseases (such as hypertension, coronary artery disease and stroke), metabolic disorders (including diabetes) as well as neurocognitive impairments like cognitive decline and an increased risk of dementia. The intricate interplay between OSA and these diverse health issues has spurred extensive research aimed at elucidating the underlying mechanisms and establishing effective interventions. Investigating the multifaceted relationships between obstructive sleep apnea and various diseases is crucial for advancing our understanding of the broader health implications of this sleep disorder and developing targeted strategies for prevention and management.

Depressive, anxiety, and sleep disturbance symptoms in patients with obstructive sleep apnea: a network analysis perspective

BMC Psychiatry, January 28, 2025
Key Finding: The obtained network model revealed notable stability and demonstrated associations among depression, anxiety, and sleep disturbance.
Read the Full Study Here

Sleep Disordered Breathing and Subsequent Neuroimaging Markers of Brain Health in Hispanic/Latino Adults

Neurology, January 14, 2025
Key Finding: Sleep disordered breathing (SDB) is a risk factor of stroke and Alzheimer disease and related dementias (ADRDs).
Read the Full Study Here

How Poor Sleep Affects your Risk of Dementia

Journal of the American Medical Association, January 1, 2021
Key Finding: Poor Sleep is a factor in Amloid Development in the Brain, which is a risk factor for dementia
Read the Full Study Here

Chronic Pain and Sleep Apnea

Science Signaling, July 30, 2024
Key Finding: The findings identify a target to potentially reduce chronic pain in patients with sleep apnea.
Read the Full Study Here

Peripheral macrophages contribute to nociceptor priming in mice with chronic intermittent hypoxia

Science Signaling, July 30, 2024
Key Finding: The hypoxic aspect of sleep apnea causes increased sensitivity to pain
Read the Full Study Here

Evaluating the Clinical Performance of a Novel, Precision Oral Appliance Therapy

Cureus, December 1, 2023
Key Finding: 89% of Patient were treated effectively with an Oral Device
Read the Full Study Here

Assessing precision oral appliance efficacy using frequency and risk based indices

Sleep, May 1, 2023
Key Finding: Precision Oral Appliance Therapy significantly improved Sleep Apnea Specific Hypoxic Burden
Read the Full Study Here

Mandibular Advancement vs. CPAP for Blood Pressure Reduction in Patients with Obstructive Sleep Apnea

Journal of the American College of Cardiology, May 1, 2024
Key Finding: Oral Devices equal to CPAP for Reducing Blood Pressure
Read the Full Study Here

Health Outcomes of CPAP vs. Oral Appliance

American Journal of Respiratory and Critical Care Medicine
Key Finding: Important health outcomes were similar after 1 month of optimal Mandibular Advancement Device and CPAP treatment
Read the Full Study Here

CPAP for prevention of Cardiovascular Events in Obstructive Sleep Apnea

The New England Journal of Medicine, September 8, 2016
Key Finding: CPAP did not prevent cardiovascular events in patients with moderate to severe OSA.
Read the Full Study Here

CPAP Therapy Termination Rates by OSA Phenotype

Journal of Clinical Medicine, March 1, 2021
Key Finding: Around 50% of CPAP users end up terminating treatment. We need non-CPAP Therapies for OSA.
Read the Full Study Here

Association between self-reported snoring and hypertension: a systematic review and meta-analysis

Sleep Medicine, December 1, 2021
Key Finding: Snoring significantly increased the risk of hypertension in both men and women
Read the Full Study Here

Snoring Is Associated With Increased Risk of Stroke, A Cumulative Meta-Analysis

Frontiers in Neurology, April 1, 2021
Key Finding: Snoring is associated with up to a 46% increased risk of stroke.
Read the Full Study Here

Snoring Is Associated With Increased Risk of Stroke

Frontiers in Neurology, April 1, 2021
Key Finding: Snoring is associated with up to a 46% increased risk of stroke.
Read the Full Study Here

Association of Sleep-disordered Breathing and the Occurrence of Stroke

American Journal of Respiratory and Critical Care Medicine, December 1, 2005
Key Finding: There is a strong association between moderate to severe sleep-disordered breathing and prevalent stroke, independent of confounding factors.
Read the Full Study Here

Obstructive sleep apnea as a risk factor for stroke and death

New England Journal of Medicine, November 10, 2005
Key Finding: Researchers have known since 2005 that obstructive sleep apnea causes a statistically significant association with stroke or death
Read the Full Study Here

Vibration enhances interleukin-8 release in a cell model of snoring-induced airway inflammation

Sleep, October 1, 2005
Key Finding: Snoring may increase your inflammatory response [such as in allergies]
Read the Full Study Here

Vibration injury damages arterial endothelial cells

Muscle Nerve, April 1, 2002
Key Finding: Electron microscopy revealed that vibration for 9 days produced loss and thinning of endothelial cells, with activated platelets coating the exposed subendothelial tissue.
Read the Full Study Here

Habitual Snoring as a Risk Factor for Brain Infarction

Acta Neurol Scand, July 1, 1995
Key Finding: Habitual snoring carries a significant risk factor for stoke
Read the Full Study Here

Heavy snoring as a cause of Carotid Atherosclerosis

Sleep, January 9, 2008
Key Finding: Heavy snoring significantly increases the risk of carotid atherosclerosis [hardening of the arteries]
Read the Full Study Here

Long-term follow-up of a randomized controlled trial of oral appliance therapy in obstructive sleep apnea

Respiration, March 1, 2011
Key Finding: Mandibular Advancement Device shows significant reduction in number of sleep disordered breathing events
Read the Full Study Here

JCSM MATRx Study

Journal of Clinical Sleep Medicine, January 3, 2023
Key Finding: Oral Devices 96% Effective in Treatment of Mild and Moderate Sleep Apnea. 81% Effective in Treatment of Severe Sleep Apnea
Read the Full Study Here

Schedule Your Consultation

For more information about obstructive sleep apnea treatments in Roslyn Heights, New York, we invite you to schedule a one-on-one consultation at Sleep Better, Live Better Inc. with Dr. Shirley Molina. Let our dentist help you achieve a better night’s sleep by calling us at email us at info@sblbinc.com.